Ko was five shots off victor Anna Nordqvist.
Nordqvis finished at 25-under 263, two shots off the LPGA Tour record.
"Hit a lot good shots and didn't quite get rewarded for them", said Lewis, who tied for second with Ariya Jutanugarn and In Gee Chun.
"Of all the wins this is probably one of the ones that's going to be more special", she said. In the U.S. Women's Open in July, she lost a three-hole playoff to Brittany Lang after being penalized two strokes for touching the sand with her club in a fairway bunker on the second extra hole.
Lewis is winless in 66 events since June 2014 and has slipped to 14th in the world.
She added five birdies to the card in the final round before throwing in just her third bogey of the tournament - at the 72 hole - to close with a four under 68 and collect the coveted trophy.
Samsung Galaxy C7 Pro tipped to be released in India
It's likely that the price won't drop that dramatically, and might even see a slight increase, when converted for the US market. Along with those new renders, some hands-on images have also leaked out, depicting the Galaxy S8 in a unique purple color.
Wie had six birdies in a nine-hole stretch, a run she capped with a 30-foot birdie putt on the par-4 ninth and a curling 8-footer on the par-4 10th. It's been busy first week back in the United States, but just always feel special coming back here.
"If it wouldn't be for me getting an opportunity to come to Arizona State University about ten years ago, I wouldn't be here today", said Nordqvist.
"Even though I live in Florida now, this definitely feels like home. I just really want to focus on like what is under my control", said Jutanugarn.
He followed up that improved showing with a final round five-under 67 this morning to leap 39 spots on the leaderboard and claim his first top 20 finish since November. "But it's not the end of day, I still shot 61". She won at Desert Ridge in 2013 to reach No. 1, was second in 2014 and 2015 and tied for fourth past year. "Felt like I played pretty solid on the front and made two good putts on 13 and 17".
Lee jumps back into the top 100 in the world rankings, in 98th, but is not now qualified for the Masters, where he finished 17th past year.
New Zealander Lydia Ko shot a 63 on Saturday to be in a tie for seventh at 16-under 200. Park tied for fifth at the Bank of Hope Founders Cup, and won the HSBC Women's Champions in Singapore two weeks ago.